Tcr Alpha Beta / Cd19+ Depleted Haploidentical Hematopoietic Progenitor Cell Graft
Childhood Acute Myeloid Leukemia
Explore 46 assets in Childhood Acute Myeloid Leukemia →Floatz Rating
CC45/100
Confidence
Indicative
Sponsor
Washington University School of Medicine
Modality
Cell therapy
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06158828CT.gov Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Childhood Acute Myeloid Leukemia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Tcr Alpha Beta / Cd19+ Depleted Haploidentical Hematopoietic Progenitor Cell Graft (this asset) | Washington University School of Medicine | P1/2 | CC · 45 |
| Etoposide | Joanna Yi | P3 | BBB |
| Cytarabine | Children's Oncology Group | P3 | BBB |
| Nivestim | National Cancer Institute (NCI) | P3 | BBB |
| Cyclophosphamide | Fred Hutchinson Cancer Center | P3 | BBB |
| Methotrexate | Children's Oncology Group | P3 | BBB |
| Fludarabine | National Cancer Institute (NCI) | P3 | BB |
| Cyclosporin A | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | P3 | BB |
| Romidepsin | Washington University School of Medicine | P3 | BB |
+42 more in the Childhood Acute Myeloid Leukemia cohort
Other indications for Tcr Alpha Beta / Cd19+ Depleted Haploidentical Hematopoietic Progenitor Cell Graft
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Acute Myeloid Leukemia | — | P1/2 | CC · 43 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Tcr Alpha Beta / Cd19+ Depleted Haploidentical Hematopoietic Progenitor Cell Graft in Childhood Acute Myeloid Leukemia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/tcr-alpha-beta-cd19-depleted-haploidentical-hematopoietic-progenitor-cell-graft-childhood-acute-myeloid-leukemia
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