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Tenofovir

Tropical Spastic Paraparesis

Explore 2 assets in Tropical Spastic Paraparesis →
Floatz Rating
CCC53/100
Confidence
Indicative
v0.2
Sponsor
Carlos Brites
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
NCT07555431CT.gov
Dolutegravir Versus Dolutegravir in Combination With Tenofovir for the Treatment of HTLV-1 Infection
—Recruiting———

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Tropical Spastic Paraparesis

AssetSponsorPhaseRating
Tenofovir (this asset)Carlos BritesP2CCC · 53
DolutegravirCarlos BritesP2CCC

Other indications for Tenofovir

IndicationSponsorPhaseRating
Hepatitis B Virus Infection—P4BB · 71
Lipodystrophy—P4BB · 66
Cardiovascular Disorder—P4BB · 66

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Tenofovir in Tropical Spastic Paraparesis. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/tenofovir-tropical-spastic-paraparesis

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