Tetrathiomolybdate
Colorectal Carcinoma
Floatz Rating
CCC54/100
Confidence
Indicative
Sponsor
University of Michigan Rogel Cancer Center
Modality
UNKNOWN
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00176774CT.gov Irinotecan, 5-Fluorouracil, and Leucovorin in Colorectal Carcinoma | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
73High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Colorectal Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Tetrathiomolybdate (this asset) | University of Michigan Rogel Cancer Center | P2 | CCC · 54 |
| Tipiracil | Mayo Clinic | P2 | BBB |
| Fluorouracilum | City of Hope Medical Center | P4 | BB |
| Oxaliplatin | First Affiliated Hospital of Zhejiang University | P4 | BB |
| Muamycin | City of Hope Medical Center | P3 | BB |
| Capecitabine | First Affiliated Hospital of Zhejiang University | P4 | BB |
| Pentoxifylline | Tanta University | P4 | BB |
| Irinotecan | City of Hope Medical Center | P3 | BB |
| Cetuximab | Shanghai Changzheng Hospital | P3 | BB |
+42 more in the Colorectal Carcinoma cohort
Other indications for Tetrathiomolybdate
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Primary Biliary Cholangitis | — | P3 | BB · 64 |
| Wilson Disease | — | P3 | B · 62 |
| Hepatocellular Carcinoma | — | P2 | B · 57 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Citation
Floatz Terminal. Tetrathiomolybdate in Colorectal Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 13, 2026. https://terminal.floatz.ai/assets/tetrathiomolybdate-colorectal-carcinoma
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