Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Cardenal Herrera University
Modality
protein_peptide
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07309094CT.gov Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKD | — | Recruiting | — | — | — |
NCT05536804CT.gov A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Chronic Kidney Disease
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Tirzepatide (this asset) | Cardenal Herrera University | P2 | CCC · 53 |
| Sodium Ferric Gluconate | Watson Pharmaceuticals | P4 | BBB |
| Semaglutide | Institute of Liver and Biliary Sciences, India | P4 | BBB |
| Iron(Ii) Sulphate (1:1), Heptahydrate | Watson Pharmaceuticals | P4 | BBB |
| Clopidogrel | Hospital Alemão Oswaldo Cruz | P4 | BB |
| Aspirin | Hospital Alemão Oswaldo Cruz | P4 | BB |
| Retatrutide | Eli Lilly and Company | P3 | BB |
| Dabigatran Etexilate | Irina Ermolaeva | P4 | BB |
| Cilostazol | Kyunghee University Medical Center | P4 | BB |
+42 more in the Chronic Kidney Disease cohort
Other indications for Tirzepatide
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Type 1 Diabetes Mellitus | — | P4 | BBB · 78 |
| Psoriatic Arthritis | — | P4 | BBB · 74 |
| Diastolic Heart Failure | — | P4 | BBB · 74 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Tirzepatide in Chronic Kidney Disease. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/tirzepatide-chronic-kidney-disease
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