Tolinapant
Fallopian Tube Serous Adenocarcinoma
Explore 29 assets in Fallopian Tube Serous Adenocarcinoma →Floatz Rating
CC47/100
Confidence
Indicative
Sponsor
National Cancer Institute (NCI)
Modality
UNKNOWN
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06393751CT.gov Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer | — | Withdrawn | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Fallopian Tube Serous Adenocarcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Tolinapant (this asset) | National Cancer Institute (NCI) | P1/2 | CC · 47 |
| Carboplatin | National Cancer Institute (NCI) | P3 | BBB |
| Olaparib | NRG Oncology | P3 | BBB |
| Cis-Diamminedichloroplatinum Ii | Ohio State University Comprehensive Cancer Center | P3 | BB |
| Adriamycin | National Cancer Institute (NCI) | P2/3 | BB |
| Nogitecan | National Cancer Institute (NCI) | P3 | BB |
| Cyclophosphamide | Roswell Park Cancer Institute | P2 | BB |
| Cediranib | National Cancer Institute (NCI) | P2/3 | BB |
| Multi-Epitope Folate Receptor Alpha-Loaded Dendritic Cell Vaccine | Mayo Clinic | P2 | BB |
+31 more in the Fallopian Tube Serous Adenocarcinoma cohort
Other indications for Tolinapant
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Ovarian Serous Adenocarcinoma | — | P1/2 | CC · 47 |
| Fallopian Tube Carcinoma | — | P1/2 | CC · 47 |
| Ovarian Carcinoma | — | P1/2 | CC · 47 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Tolinapant in Fallopian Tube Serous Adenocarcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/tolinapant-fallopian-tube-serous-adenocarcinoma
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