Floatz Rating
B57/100
Confidence
Indicative
Sponsor
Topas Therapeutics GmbH
Modality
UNKNOWN
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05660109CT.gov A Study to Assess the Safety of TPM502 in Adults With Celiac Disease | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Celiac Disease
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| tpm502 (this asset) | Topas Therapeutics GmbH | P2 | B · 57 |
| Necator Americanus | James Cook University, Queensland, Australia | P2 | BB |
| Macrogols | Sheffield Teaching Hospitals NHS Foundation Trust | P4 | BB |
| Larazotide | 9 Meters Biopharma, Inc. | P3 | BB |
| Latiglutenase | Entero Therapeutics | P2 | BB |
| Prolyl Endopeptidase | Dr. C. Bonorino Udaondo Gastroenterology Hospital | P4 | BB |
| Simvastatin | Entero Therapeutics | P2/3 | BB |
| Prucalopride | University of British Columbia | P4 | BB |
| Vivomixx | University of Milan | P4 | BB |
+42 more in the Celiac Disease cohort
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. tpm502 in Celiac Disease. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/tpm502-celiac-disease
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