Floatz Rating
CC44/100
Confidence
Indicative
Sponsor
Tempest Therapeutics
Modality
UNKNOWN
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03829436CT.gov TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Gastroesophageal Cancer
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Tpst-1120 (this asset) | Tempest Therapeutics | P1 | CC · 44 |
| Carboplatin | Iambic Therapeutics, Inc | P1/2 | B |
| Oxaliplatin | Incyte Corporation | P1/2 | B |
| Fluorouracilum | Incyte Corporation | P1/2 | B |
| Pembrolizumab | Diwakar Davar | P2 | B |
| Cyclophosphamide | Diwakar Davar | P2 | B |
| Docetaxel | Oscotec Inc. | P2 | B |
| Nivolumab | Shanghai Henlius Biotech | P2 | B |
| Cis-Diamminedichloroplatinum Ii | Incyte Corporation | P1/2 | B |
+42 more in the Gastroesophageal Cancer cohort
Other indications for Tpst-1120
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Hepatocellular Carcinoma | — | P3 | B · 56 |
| Head And Neck Squamous Cell Carcinoma | — | P1 | CC · 44 |
| Triple-Negative Breast Carcinoma | — | P1 | CC · 44 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Tpst-1120 in Gastroesophageal Cancer. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/tpst-1120-gastroesophageal-cancer
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