Floatz Rating
B56/100
Confidence
Indicative
Sponsor
National Cancer Institute (NCI)
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
41Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02042443CT.gov Trametinib or Combination Chemotherapy in Treating Patients With Refractory or Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed by Surgery | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Gallbladder Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Trametinib (this asset) | National Cancer Institute (NCI) | P2 | B · 56 |
| Fluorouracilum | Lisata Therapeutics, Inc. | P2 | B |
| Cis-Diamminedichloroplatinum Ii | Lisata Therapeutics, Inc. | P2 | B |
| Pembrolizumab | Seagen, a wholly owned subsidiary of Pfizer | P2 | B |
| Durvalumab | Lisata Therapeutics, Inc. | P2 | B |
| Immunoglobulin G1, Anti-(Human Vascular Endothelial Growth Factor Receptor Type Vegfr-2 Extracellular Domain) (Human Monoclonal Imc-1121B .Gamma.-Chain), Disulphide With Human Monoclonal Imc-1121B .Kappa.-Chain, Dimer | M.D. Anderson Cancer Center | P2 | B |
| Oxaliplatin | Lisata Therapeutics, Inc. | P2 | B |
| Capecitabine | Seagen, a wholly owned subsidiary of Pfizer | P2 | B |
| Nivolumab | National Cancer Institute (NCI) | P2 | B |
+28 more in the Gallbladder Carcinoma cohort
Other indications for Trametinib
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Melanoma | — | P4 | BB · 69 |
| Anaplastic Pleomorphic Xanthoastrocytoma | — | P4 | BB · 69 |
| Anaplastic Oligodendroglioma | — | P4 | BB · 69 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- FluorouracilumLisata Therapeutics, Inc.B
- Cis-Diamminedichloroplatinum IiLisata Therapeutics, Inc.B
- PembrolizumabSeagen, a wholly owned subsidiary of PfizerB
- DurvalumabLisata Therapeutics, Inc.B
- Immunoglobulin G1, Anti-(Human Vascular Endothelial Growth Factor Receptor Type Vegfr-2 Extracellular Domain) (Human Monoclonal Imc-1121B .Gamma.-Chain), Disulphide With Human Monoclonal Imc-1121B .Kappa.-Chain, DimerM.D. Anderson Cancer CenterB
Citation
Floatz Terminal. Trametinib in Gallbladder Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/trametinib-gallbladder-carcinoma
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