Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Peking University People's Hospital
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07586813CT.gov Romiplostim N01 Plus ATRA for Persistent Isolated Chemotherapy-Induced Thrombocytopenia After Complete Remission of Gastrointestinal Solid Tumors | — | Recruiting | — | — | — |
NCT07586826CT.gov Romiplostim N01 Plus ATRA for Persistent Isolated Chemotherapy-Induced Thrombocytopenia After Complete Remission of Gynecologic, Breast, or Lung Solid Tumors | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Thrombocytopenia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Tretinoin (this asset) | Peking University People's Hospital | P2 | CCC · 53 |
| Recombinant Human Thrombopoietin | Sun Yat-sen University | P4 | BBB |
| Eltrombopag | Institute of Hematology & Blood Diseases Hospital, China | P4 | BB |
| Avatrombopag | Second Affiliated Hospital of Guangzhou Medical University | P4 | BB |
| Nivestim | OHSU Knight Cancer Institute | P2 | BB |
| Hetrombopag | Sun Yat-sen University | P3 | BB |
| Cytarabine | OHSU Knight Cancer Institute | P2 | BB |
| Cyclosporin A | Children's Hospital Los Angeles | P2 | BB |
| Prednisone | Children's Hospital Los Angeles | P2 | BB |
+42 more in the Thrombocytopenia cohort
Other indications for Tretinoin
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Acute Promyelocytic Leukemia | — | P4 | A · 82 |
| Myelodysplastic/Myeloproliferative Neoplasm | — | P3 | BB · 69 |
| Acute Myeloid Leukemia | — | P3 | BB · 67 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Tretinoin in Thrombocytopenia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/tretinoin-thrombocytopenia
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