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Tsha-105

Developmental And Epileptic Encephalopathy, 25

Explore 1 assets in Developmental And Epileptic Encephalopathy, 25
Floatz Rating
CCC48/100
Confidence
Indicative
v0.2
Sponsor
TESS Research Foundation
Modality
gene_therapy
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Intrathecal Gene Therapy For SLC13A5 Citrate Transporter Disorder
Not Yet Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Developmental And Epileptic Encephalopathy, 25

AssetSponsorPhaseRating
Tsha-105 (this asset)TESS Research FoundationP1/2CCC · 48

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Citation

Floatz Terminal. Tsha-105 in Developmental And Epileptic Encephalopathy, 25. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/tsha-105-developmental-and-epileptic-encephalopathy-25

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