Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Zhen Wang, MD
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04258462CT.gov Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Renal Tumors | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Renal Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Urea (this asset) | Zhen Wang, MD | P2 | CCC · 53 |
| Nivolumab | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | P4 | BBB |
| Cabozantinib | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | P4 | BB |
| Pembrolizumab | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | P4 | BB |
| Ipilimumab | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | P4 | BB |
| Marcaine | Wake Forest University Health Sciences | P3 | B |
| Axitinib | Gustave Roussy, Cancer Campus, Grand Paris | P3 | B |
| Ropivacaine | Wake Forest University Health Sciences | P3 | B |
| Epinephrine | Wake Forest University Health Sciences | P3 | B |
+42 more in the Renal Carcinoma cohort
Other indications for Urea
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Radiodermatitis | — | P3 | BB · 69 |
| Hepatocellular Carcinoma | — | P4 | B · 63 |
| Cancer Of Unknown Primary Site | — | P3 | B · 62 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- NivolumabFondazione Policlinico Universitario Agostino Gemelli IRCCSBBB
- CabozantinibFondazione Policlinico Universitario Agostino Gemelli IRCCSBB
- PembrolizumabFondazione Policlinico Universitario Agostino Gemelli IRCCSBB
- IpilimumabFondazione Policlinico Universitario Agostino Gemelli IRCCSBB
- MarcaineWake Forest University Health SciencesB
Citation
Floatz Terminal. Urea in Renal Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/urea-renal-carcinoma
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