Venetoclax
Acute Myeloid Leukemia By FAB Classification
Explore 16 assets in Acute Myeloid Leukemia By FAB Classification →Floatz Rating
B57/100
Confidence
Indicative
Sponsor
University Hospital, Caen
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05262465CT.gov Microtransplantation Combined With Azacytidine to Improve the Efficacy of EAML | — | Unknown | — | — | — |
NCT03226418CT.gov Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia | — | Completed | — | — | — |
NCT02115295CT.gov Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Acute Myeloid Leukemia By FAB Classification
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Venetoclax (this asset) | University Hospital, Caen | P2 | B · 57 |
| Daunomycin | Wake Forest University Health Sciences | P3 | BBB |
| Idarubicin | University of Nebraska | P3 | BB |
| 2 (1H))-QUINOLINONE,6-(AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-4-(3-CHLOROPHENYL)-1-METHYL-,(+)- | National Cancer Institute (NCI) | P3 | BB |
| Valspodar | National Cancer Institute (NCI) | P3 | BB |
| Mercaptopurine Anhydrous | Roswell Park Cancer Institute | P3 | BB |
| Azacitidine | guomei | P2 | BB |
| Caspofungin | Children's Oncology Group | P3 | BB |
| Fluconazole | Children's Oncology Group | P3 | BB |
+41 more in the Acute Myeloid Leukemia By FAB Classification cohort
Other indications for Venetoclax
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | — | P4 | BB · 70 |
| Acute Myeloid Leukemia | — | P4 | BB · 69 |
| Chronic Myelomonocytic Leukemia | — | P2/3 | BB · 68 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- DaunomycinWake Forest University Health SciencesBBB
- IdarubicinUniversity of NebraskaBB
- 2 (1H))-QUINOLINONE,6-(AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-4-(3-CHLOROPHENYL)-1-METHYL-,(+)-National Cancer Institute (NCI)BB
- ValspodarNational Cancer Institute (NCI)BB
- Mercaptopurine AnhydrousRoswell Park Cancer InstituteBB
Citation
Floatz Terminal. Venetoclax in Acute Myeloid Leukemia By FAB Classification. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/venetoclax-acute-myeloid-leukemia-by-fab-classification
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