Venetoclax
Acute Myeloid Leukemia, FLT3 Internal Tandem Duplication
Explore 10 assets in Acute Myeloid Leukemia, FLT3 Internal Tandem Duplication →Floatz Rating
B60/100
Confidence
Indicative
Sponsor
First Affiliated Hospital of Zhejiang University
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
45Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07259707CT.gov Gilteritinib Plus VA Followed By Consolidation Chemotherapy in Newly Diagnosed FLT3-ITD+ AML | — | Recruiting | — | — | — |
NCT03735875CT.gov Venetoclax and Quizartinib in Treating Patients With FLT3-mutated Recurrent or Refractory Acute Myeloid Leukemia | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Acute Myeloid Leukemia, FLT3 Internal Tandem Duplication
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Venetoclax (this asset) | First Affiliated Hospital of Zhejiang University | P2 | B · 60 |
| Gilteritinib | The First Affiliated Hospital of Soochow University | P3 | BB |
| Azacitidine | French Innovative Leukemia Organisation | P2 | BB |
| Cytarabine | First Affiliated Hospital of Zhejiang University | P3 | BB |
| Sorafenib | The First Affiliated Hospital of Soochow University | P3 | BB |
| Daunomycin | Gruppo Italiano Malattie EMatologiche dell'Adulto | P3 | BB |
| xy0206 | Shijiazhuang Yiling Pharmaceutical Co. Ltd | P3 | BB |
| Quizartinib | M.D. Anderson Cancer Center | P2 | BB |
| Fludarabine | Astellas Pharma Global Development, Inc. | P2 | B |
+13 more in the Acute Myeloid Leukemia, FLT3 Internal Tandem Duplication cohort
Other indications for Venetoclax
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | — | P4 | BB · 70 |
| Acute Myeloid Leukemia | — | P4 | BB · 69 |
| Chronic Myelomonocytic Leukemia | — | P2/3 | BB · 68 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- GilteritinibThe First Affiliated Hospital of Soochow UniversityBB
- AzacitidineFrench Innovative Leukemia OrganisationBB
- CytarabineFirst Affiliated Hospital of Zhejiang UniversityBB
- SorafenibThe First Affiliated Hospital of Soochow UniversityBB
- DaunomycinGruppo Italiano Malattie EMatologiche dell'AdultoBB
Citation
Floatz Terminal. Venetoclax in Acute Myeloid Leukemia, FLT3 Internal Tandem Duplication. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/venetoclax-acute-myeloid-leukemia-flt3-internal-tandem-duplication
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