Floatz Rating
CC44/100
Confidence
Indicative
Sponsor
Vanda Pharmaceuticals
Modality
UNKNOWN
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06494397CT.gov Pharmacokinetic Study of VHX-896 and Iloperidone Tablets Under Steady-State Conditions | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Bipolar I Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Vhx-896 (this asset) | Vanda Pharmaceuticals | P1 | CC · 44 |
| Lurasidone | Massachusetts General Hospital | P4 | BBB |
| Lithium, Elemental | Alzamend Neuro, Inc. | P4 | BBB |
| Escitalopram | Massachusetts General Hospital | P4 | BBB |
| Olanzapine | Alkermes, Inc. | P4 | BBB |
| Asenapine | Organon and Co | P3 | BBB |
| Lamotrigine | Bristol-Myers Squibb | P4 | BBB |
| Cariprazine | Pakistan Institute of Medical Sciences | P4 | BBB |
| Iloperidone | Vanda Pharmaceuticals | P4 | BBB |
+42 more in the Bipolar I Disorder cohort
Other indications for Vhx-896
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Schizophrenia | — | P1 | CC · 40 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Vhx-896 in Bipolar I Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/vhx-896-bipolar-i-disorder
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