Vincristine Sulfate
Refractory Precursor T-Lymphoblastic Lymphoma/Leukemia
Explore 27 assets in Refractory Precursor T-Lymphoblastic Lymphoma/Leukemia →Floatz Rating
CCC48/100
Confidence
Indicative
Sponsor
ECOG-ACRIN Cancer Research Group
Modality
Small molecule
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03504644CT.gov Venetoclax and Vincristine in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Refractory Precursor T-Lymphoblastic Lymphoma/Leukemia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Vincristine Sulfate (this asset) | ECOG-ACRIN Cancer Research Group | P1/2 | CCC · 48 |
| Dexasone | Princess Maxima Center for Pediatric Oncology | P1/2 | CCC |
| Prednisolone | Children's Oncology Group | P1/2 | CCC |
| Hydrocortisone | Children's Oncology Group | P1/2 | CCC |
| Rituximab | M.D. Anderson Cancer Center | P1/2 | CCC |
| Prednisone | M.D. Anderson Cancer Center | P1/2 | CCC |
| Nelarabine | M.D. Anderson Cancer Center | P1/2 | CCC |
| Obi 3424 | SWOG Cancer Research Network | P1/2 | CCC |
| Mercaptopurine Anhydrous | M.D. Anderson Cancer Center | P1/2 | CCC |
+26 more in the Refractory Precursor T-Lymphoblastic Lymphoma/Leukemia cohort
Other indications for Vincristine Sulfate
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| B-Cell Childhood Acute Lymphoblastic Leukemia | — | P3 | A · 81 |
| Diffuse Large B-Cell Lymphoma | — | P2/3 | A · 80 |
| Childhood Acute Lymphoblastic Leukemia | — | P3 | BBB · 76 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Vincristine Sulfate in Refractory Precursor T-Lymphoblastic Lymphoma/Leukemia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/vincristine-sulfate-refractory-precursor-t-lymphoblastic-lymphomaleukemia
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