Floatz Rating
CC41/100
Confidence
Indicative
Sponsor
Memorial Sloan Kettering Cancer Center
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07223034CT.gov A Study of 177Lu-PSMA-617 in People With Gliomas | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · IDH-Wildtype Glioblastoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Vipivotide Tetraxetan (this asset) | Memorial Sloan Kettering Cancer Center | P1 | CC · 41 |
| Immunoglobulin G4, Anti-(Human Programmed Cell Death Protein 1) (Human Monoclonal Regn2810 Heavy Chain), Disulfide With Human Monoclonal Regn2810 .Kappa.-Chain, Dimer | National Cancer Institute (NCI) | P2 | B |
| Ipilimumab | Neonc Technologies, Inc. | P2 | B |
| Pembrolizumab | Mayo Clinic | P2 | B |
| Nivolumab | Neonc Technologies, Inc. | P2 | B |
| Cerebraca Wafer | Everfront Biotech Co., Ltd. | P2/3 | B |
| Lomustine | Vastra Gotaland Region | P3 | B |
| Atezolizumab | National Cancer Institute (NCI) | P2 | CCC |
| Adriamycin | Northwestern University | P2 | CCC |
+36 more in the IDH-Wildtype Glioblastoma cohort
Other indications for Vipivotide Tetraxetan
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Prostate Adenocarcinoma | — | P3 | BB · 67 |
| Renal Cell Carcinoma | — | P3 | BB · 66 |
| Prostate Carcinoma | — | P2 | BB · 64 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- Immunoglobulin G4, Anti-(Human Programmed Cell Death Protein 1) (Human Monoclonal Regn2810 Heavy Chain), Disulfide With Human Monoclonal Regn2810 .Kappa.-Chain, DimerNational Cancer Institute (NCI)B
- IpilimumabNeonc Technologies, Inc.B
- PembrolizumabMayo ClinicB
- NivolumabNeonc Technologies, Inc.B
- Cerebraca WaferEverfront Biotech Co., Ltd.B
Citation
Floatz Terminal. Vipivotide Tetraxetan in IDH-Wildtype Glioblastoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/vipivotide-tetraxetan-idh-wildtype-glioblastoma
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