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Floatz Rating
CCC50/100
Confidence
Indicative
v0.2
Sponsor
Global Coalition for Adaptive Research
Modality
UNKNOWN
Development Phase
Phase 2/3
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Glioblastoma

AssetSponsorPhaseRating
vt1021 (this asset)Global Coalition for Adaptive ResearchP2/3CCC · 50
Depatuxizumab MafodotinAbbVieP3BB
Cintredekin BesudotoxINSYS Therapeutics IncP3BB
CamustineLeland MethenyP3BB
(+)-VincristineUniversity of CincinnatiP3BB
IrinotecanUniversity of CincinnatiP3BB
CapecitabineNorthwell HealthP2BB
LomustineTelix Pharmaceuticals (Innovations) Pty LimitedP3BB
CarboplatinSichuan Honghe Biotechnology Co., Ltd.P3BB

+42 more in the Glioblastoma cohort

Other indications for vt1021

IndicationSponsorPhaseRating
NeoplasmP1C · 36

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. vt1021 in Glioblastoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/vt1021-glioblastoma

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