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Xer-001

Pancreatic Ductal Adenocarcinoma

Explore 280 assets in Pancreatic Ductal Adenocarcinoma
Floatz Rating
CC47/100
Confidence
Indicative
v0.2
Sponsor
Xerient Pharma
Modality
UNKNOWN
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Pancreatic Ductal Adenocarcinoma

AssetSponsorPhaseRating
Xer-001 (this asset)Xerient PharmaP1/2CC · 47
Immunoglobulin G2, Anti-(Human Ctla-4 (Antigen)) (Human Monoclonal Cp-675206 Clone 11.2.1 Heavy Chain) Disulphide With Human Monoclonal Cp-675206 Clone 11.2.1 Light Chain, DimerOHSU Knight Cancer InstituteP2BB
Rmc-6236Tango Therapeutics, Inc.P3BB
DaraxonrasibRevolution Medicines, Inc.P3BB
S-1Genentech, Inc.P2BB
MetforminBritish Columbia Cancer AgencyP2BB
(R)-(1-(4-Fluorophenyl)-6-((1-Methyl-1H-Pyrazol-4-Yl)Sulfonyl)-1,4,5,6,7,8-Hexahydro-4Ah-Pyrazolo(3,4-G)Isoquinolin-4A-Yl)(4-(Trifluoromethyl)Pyridin-2-Yl)MethanoneCorcept TherapeuticsP3BB
IvospeminPanbela Therapeutics, Inc.P2/3BB
OxaliplatinJonsson Comprehensive Cancer CenterP4BB

+42 more in the Pancreatic Ductal Adenocarcinoma cohort

Other indications for Xer-001

IndicationSponsorPhaseRating
Pancreatic AdenocarcinomaP1/2CC · 45
Malignant Pancreatic NeoplasmP1/2NR

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Xer-001 in Pancreatic Ductal Adenocarcinoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/xer-001-pancreatic-ductal-adenocarcinoma

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