Yohimbine
Developmental Disorder Of Mental Health
Explore 1 assets in Developmental Disorder Of Mental Health →Floatz Rating
D30/100
Confidence
Indicative
Sponsor
Charite University, Berlin, Germany
Modality
Small molecule
Development Phase
N/A
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
15Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02470026CT.gov Noradrenergic Activity, Cognition and Major Depressive Disorder | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Developmental Disorder Of Mental Health
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Yohimbine (this asset) | Charite University, Berlin, Germany | N/A | D · 30 |
| Lumateperone | University of Texas at Austin | P4 | BB |
| Human Immunoglobulins | National Institute of Mental Health (NIMH) | P3 | B |
Other indications for Yohimbine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Melancholia | — | P2 | B · 57 |
| Major Depressive Disorder | — | P2 | CCC · 51 |
| Parkinson Disease | — | Early P1 | C · 34 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Yohimbine in Developmental Disorder Of Mental Health. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/yohimbine-developmental-disorder-of-mental-health
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