Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
UNICANCER
Modality
monoclonal_antibody
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07192068CT.gov Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene. | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Endometrial Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Zanidatamab (this asset) | UNICANCER | P2 | CCC · 53 |
| Semaglutide | Washington University School of Medicine | P2 | CCC |
| Levonorgestrel | Washington University School of Medicine | P2 | CCC |
| Pasifolate Exatecan | Elucida Oncology | P1/2 | CCC |
| Capecitabine | Western Regional Medical Center | P1/2 | CCC |
| Irinotecan | Western Regional Medical Center | P1/2 | CCC |
| Temsirolimus | Western Regional Medical Center | P1/2 | CCC |
| Nivolumab | Western Regional Medical Center | P1/2 | CCC |
| Fulvestrant | Pfizer | P1 | CC |
+4 more in the Endometrial Disorder cohort
Other indications for Zanidatamab
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| HER2 Positive Breast Carcinoma | — | P3 | BB · 65 |
| Breast Carcinoma | — | P2 | BB · 64 |
| Gastric Neoplasm | — | P3 | B · 60 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Zanidatamab in Endometrial Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/zanidatamab-endometrial-disorder
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