Floatz Rating
B61/100
Confidence
Indicative
Sponsor
Lindner Center of HOPE
Modality
Small molecule
Development Phase
Phase 3
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
46Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00221442CT.gov Zonegran in the Treatment of Binge Eating Disorder Associated With Obesity | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Binge Eating Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Zonisamide (this asset) | Lindner Center of HOPE | P3 | B · 61 |
| Sibutramine | Yale University | P4 | BBB |
| Liraglutide | Universiti Kebangsaan Malaysia Medical Centre | P4 | BB |
| Topiramate | University of Virginia | P3 | BB |
| Memantine | Mclean Hospital | P4 | BB |
| Orlistat | Yale University | P4 | BB |
| Armodafinil | Lindner Center of HOPE | P3 | BB |
| Lamotrigine | Lindner Center of HOPE | P3 | BB |
| Pramipexole | Neuropsychiatric Research Institute, Fargo, North Dakota | P3 | B |
+4 more in the Binge Eating Disorder cohort
Other indications for Zonisamide
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Focal Epilepsy | — | P4 | BBB · 74 |
| Epilepsy | — | P4 | BB · 69 |
| Migraine Disorder | — | P4 | B · 63 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Zonisamide in Binge Eating Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/zonisamide-binge-eating-disorder
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