253 assets in Diffuse Large B-Cell Lymphoma

Gardasil 9 Vaccine

Mb-Cart2019.1

Mirabegron

Ontorpacept

Plamotamab

Plerixafor

Sepantronium

Treosulfan

Trilaciclib

Wztl-002 Car T-Cells

Zuberitamab

Apamistamab

Parsaclisib

Tamoxifen

1-118-Signal regulatory protein ? (human) fusion protein with immunoglobulin G4 [128-proline] (human ?4-chain C region C-terminal fragment), dimer

cd19/cd22-bispecific car-t cells

Chir-Del

Emapalumab

Hyaluronidase

Iopofosine (¹³¹I)

Loncastuximab Tesirine

Penpulimab

Tofacitinib

Allo-Quadcar01-T

Bgb-16673

Retifanlimab

Baff-R Car-T

Idp-121

Immunoglobulin G1, Anti-(Human Programmed Death-Ligand 1) (Human Monoclonal Sti-3031 .Gamma.1-Chain), Disulfide With Human Monoclonal Sti-3031 .Lambda.-Chain, Dimer

Itacitinib

Mrt-2359

RNK05047

ace1831

Aleta-001

crc01

hdm2005

Lacutoclax

mdx2003

mk-1045

Prizloncabtagene Autoleucel

tc011

Immunoglobulin G1, Anti-(Human Cd Antigen Cd27) (Human Monoclonal Cdx-1127 Clone 1F5 Heavy Chain), Disulfide With Human Monoclonal Cdx-1127 Clone 1F5 .Kappa.-Chain, Dimer

prt2527

1928z1xx trac t cell

Allogenic Ex Vivo Expanded Natural Killer Cells

Anti-Cd30 Bispecific Antibody-Armed Anti-Cd3-Activated Autologous T-Cells

Autologous Cd19Car-Cd28-Cd3Zeta-Egfrt-Expressing Tcm-Enriched T Cells

Autologous T Cells Obtained From Peripheral Blood Mononuclear Cells By Leukapheresis, Transduced With A Self-Inactivating, Nonreplicating Lentiviral Vector, Encoding A T Cell Chimeric Antigen Receptor Targeting Cd19. The Expressed Transgene Comprises A Cd8? Leader Sequence, A Murine Anti-Cd19 Single Chain Variable Fragment (Scfv) Derived From The Mouse Hybridoma Fmc63, A Cd8? Hinge And Transmembrane Region, And A 4-1Bb (Cd137) And Cd3? (Tcr?) Signaling Domain And Is Under Control Of The Elongation Factor 1 Alpha (Ef1?) Promoter. The Construct Is Flanked By 5' And 3' Long Terminal Repeats (Ltrs) And Also Contains A ? Packaging Signal, A Rev Response Element (Rre), A Central Polypurine Tract (Cppt) Sequence And An Optimized Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element (Wpre). The Leukapheresis Material Is Enriched For Cd4/Cd8 T Cells By Positive Immunoselection, Activated By Cd3 And Cd28 Agonists And Transduced With The Vector. Without Further Cell Propagation, The T Cells Are Washed, Formulated For Infusion, And Cryopreserved. The Substance Is Composed Of ?80% T Cells And ?1% B Cells, With A Mixture Of Transgene Positive (>3.4%) And Negative T Cells. The Cd4+ And Cd8+ Naïve T Cell Subsets (Cd45Ra+Ccr7+) Present In The Leukapheresis Material Are Largely Retained

bn301

BP1002