ad5-ycd/muttksr39rep-adp adenovirus
Anaplastic Astrocytoma
Explore 35 assets in Anaplastic Astrocytoma →Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
Henry Ford Health System
Modality
gene_therapy
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05686798CT.gov Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma. | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Anaplastic Astrocytoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| ad5-ycd/muttksr39rep-adp adenovirus (this asset) | Henry Ford Health System | P1 | CC · 43 |
| Irinotecan | City of Hope Medical Center | P2/3 | BBB |
| Cediranib | National Cancer Institute (NCI) | P2 | BBB |
| (+)-Vincristine | Novartis Pharmaceuticals | P2/3 | BB |
| Carboplatin | Oliver Jonas | P2 | BB |
| Cintredekin Besudotox | INSYS Therapeutics Inc | P1/2 | BB |
| Trametinib | National Cancer Institute (NCI) | P4 | BB |
| Ziv-Aflibercept | National Cancer Institute (NCI) | P2 | B |
| Dabrafenib | National Cancer Institute (NCI) | P4 | B |
+42 more in the Anaplastic Astrocytoma cohort
Other indications for ad5-ycd/muttksr39rep-adp adenovirus
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Brain Glioma | — | P1 | CC · 43 |
| Astrocytic Tumor | — | P1 | CC · 43 |
| Non-Small Cell Lung Carcinoma | — | P1 | CC · 43 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. ad5-ycd/muttksr39rep-adp adenovirus in Anaplastic Astrocytoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ad5-ycdmuttksr39rep-adp-adenovirus-anaplastic-astrocytoma
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