Anti-Mesothelin Chimeric T Cell Receptor Transduced Peripheral Blood Lymphocytes
Cervical Cancer
Explore 159 assets in Cervical Cancer →Floatz Rating
CC41/100
Confidence
Indicative
Sponsor
National Cancer Institute (NCI)
Modality
Cell therapy
Development Phase
Phase 1/2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT01583686CT.gov CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Cervical Cancer
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Anti-Mesothelin Chimeric T Cell Receptor Transduced Peripheral Blood Lymphocytes (this asset) | National Cancer Institute (NCI) | P1/2 | CC · 41 |
| Vinorelbine Ditartrate | UNICANCER | P2 | BB |
| Tisotumab Vedotin | Seagen Inc. | P2 | BB |
| Carboplatin | Merck Sharp & Dohme LLC | P3 | B |
| Cis-Diamminedichloroplatinum Ii | Uganda Cancer Institute | P3 | B |
| Pembrolizumab | Merck Sharp & Dohme LLC | P3 | B |
| Cyclophosphamide | Merck Sharp & Dohme LLC | P3 | B |
| Indocyanine Green | Istanbul University | P4 | B |
| Technetium-99 | Institut de Cancérologie de Lorraine | P3 | B |
+42 more in the Cervical Cancer cohort
Other indications for Anti-Mesothelin Chimeric T Cell Receptor Transduced Peripheral Blood Lymphocytes
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Mesothelioma | — | P1/2 | CC · 43 |
| Lung Cancer | — | P1/2 | CC · 41 |
| Pancreatic Neoplasm | — | P1/2 | CC · 40 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Anti-Mesothelin Chimeric T Cell Receptor Transduced Peripheral Blood Lymphocytes in Cervical Cancer. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 14, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/anti-mesothelin-chimeric-t-cell-receptor-transduced-peripheral-blood-lymphocytes-cervical-cancer
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