Floatz Rating
B57/100
Confidence
Indicative
Sponsor
VectivBio AG
Modality
protein_peptide
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04964986CT.gov Metabolic Balance Study of Apraglutide in Patients With Short Bowel Syndrome, Intestinal Failure (SBS-IF) and Colon-in-Continuity (CIC) | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Short Bowel Syndrome
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Apraglutide (this asset) | VectivBio AG | P2 | B · 57 |
| Serostim | Northwestern University | P4 | BB |
| Glepaglutide | Zealand Pharma | P3 | B |
| Loperamide | Odense University Hospital | P3 | B |
| Mono-[2,5,7,8-Tetramethyl-2-(4,8,12-Trimethyltridecyl)-6-Chromanyl] Succinate Polyethylene Glycol Monoester | Boston Children's Hospital | P2 | CCC |
| Crofelemer | Napo Therapeutics, S.p.A. | P2 | CCC |
| Glucagon-Like Peptide 2 | Alberta Children's Hospital | P1/2 | CCC |
| fe203799 | GlyPharma Therapeutics | P1/2 | NR |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Apraglutide in Short Bowel Syndrome. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/apraglutide-short-bowel-syndrome
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