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Bardoxolone Methyl Ester

IgA Glomerulonephritis

Explore 3 assets in IgA Glomerulonephritis
Floatz Rating
B57/100
Confidence
Indicative
v0.2
Sponsor
Biogen
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · IgA Glomerulonephritis

AssetSponsorPhaseRating
Bardoxolone Methyl Ester (this asset)BiogenP2B · 57
ValsartanColumbia UniversityP4BB
PrednisoneNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)P2B
AliskirenColumbia UniversityP4CCC
Ucar T-CellThe Children's Hospital of Zhejiang University School of MedicineP1CCC
qt-219cxThe Children's Hospital of Zhejiang University School of MedicineEarly P1C
RD06-05 CART CellThe Children's Hospital of Zhejiang University School of MedicineEarly P1C
EnalaprilNational Center for Research Resources (NCRR)N/AD

Other indications for Bardoxolone Methyl Ester

IndicationSponsorPhaseRating
Pulmonary HypertensionP2B · 57
Pulmonary Arterial HypertensionP2B · 57
Interstitial Lung DiseaseP2B · 57

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Bardoxolone Methyl Ester in IgA Glomerulonephritis. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/bardoxolone-methyl-ester-iga-glomerulonephritis

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