Floatz Rating
B57/100
Confidence
Indicative
Sponsor
Eli Lilly and Company
Modality
monoclonal_antibody
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04476108CT.gov Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Diabetic Peripheral Neuropathic Pain | — | Completed | — | — | — |
NCT05986292CT.gov A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Diabetic Neuropathy
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Fepixnebart (this asset) | Eli Lilly and Company | P2 | B · 57 |
| Duloxetine | Aga Khan University | P4 | A |
| Gabapentin | Aziende Chimiche Riunite Angelini Francesco S.p.A | P4 | BBB |
| Mirogabalin | Bangladesh Medical University | P4 | BBB |
| Capsaicin | Corporacion Parc Tauli | P4 | BBB |
| Lidocaine | Corporacion Parc Tauli | P4 | BBB |
| Pregabalin | Shandong Suncadia Medicine Co., Ltd. | P4 | BBB |
| (±)-2-(O-Chlorophenyl)-2-(Methylamino)Cyclohexanone | Irmandade da Santa Casa de Misericordia de Sao Paulo | P3 | BB |
| Tapentadol | Janssen Pharmaceutical K.K. | P3 | BB |
+42 more in the Diabetic Neuropathy cohort
Other indications for Fepixnebart
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Osteoarthritis | — | P2 | B · 57 |
| Osteoarthritis, Knee | — | P2 | CCC · 53 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Fepixnebart in Diabetic Neuropathy. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/fepixnebart-diabetic-neuropathy-106578
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