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Floatz Rating
C36/100
Confidence
Indicative
v0.2
Sponsor
University of Chicago
Modality
UNKNOWN
Development Phase
Early Phase 1
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
24Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Mood Effects of Serotonin Agonists: Depression
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
73High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Depressive Disorder

AssetSponsorPhaseRating
Lsd (this asset)University of ChicagoEarly P1C · 36
BrexpiprazoleDr. Albert Kar-Kin ChungP4A
Jnj-54135419Chinese PLA General HospitalP4BBB
SaredutantSanofiP3BBB
Lithium, ElementalRakitzi, StavroulaP4BBB
EscitalopramPoznan University of Medical SciencesP4BBB
VENLORJanssen Research & Development, LLCP4BBB
FluoxetineUniversity of OxfordP4BBB
ParoxetineBrigham and Women's HospitalP4BBB

+42 more in the Depressive Disorder cohort

Other indications for Lsd

IndicationSponsorPhaseRating
Major Depressive DisorderP2B · 58
Lysosomal Storage DiseaseEarly P1C · 39

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Lsd in Depressive Disorder. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 11, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/lsd-depressive-disorder

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