Floatz Rating
C39/100
Confidence
Indicative
Sponsor
University of Chicago
Modality
UNKNOWN
Development Phase
Early Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
24Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07017478CT.gov Mood Effects of Serotonin Agonists: Depression | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Lysosomal Storage Disease
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Lsd (this asset) | University of Chicago | Early P1 | C · 39 |
| flt190 | Spur Therapeutics | P1/2 | CCC |
| Dna (Recombinant Adeno-Associated Virus Vector Aav-Spark100-Gaa Human Liver-Specific Expression Cassette Including Human Lysosomal ?-Glucosidase Codon-Optimized Gene Gaa Plus Adeno-Associated Virus 2 Inverted Terminal Repeat Flanks) | Spark Therapeutics, Inc. | P1/2 | CCC |
| Iduronidase, .Alpha.-L-(8-Histidine) (Human) | Patricia I. Dickson, M.D. | P1 | CC |
| Cyclosporin A | Masonic Cancer Center, University of Minnesota | N/A | D |
| Clofarabine | Masonic Cancer Center, University of Minnesota | N/A | D |
| Melphalan | Masonic Cancer Center, University of Minnesota | N/A | D |
| Campath-1H | Masonic Cancer Center, University of Minnesota | N/A | D |
| Ald-101 | Aldagen | P3 | NR |
Other indications for Lsd
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Major Depressive Disorder | — | P2 | B · 58 |
| Depressive Disorder | — | Early P1 | C · 36 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- flt190Spur TherapeuticsCCC
- Dna (Recombinant Adeno-Associated Virus Vector Aav-Spark100-Gaa Human Liver-Specific Expression Cassette Including Human Lysosomal ?-Glucosidase Codon-Optimized Gene Gaa Plus Adeno-Associated Virus 2 Inverted Terminal Repeat Flanks)Spark Therapeutics, Inc.CCC
- Iduronidase, .Alpha.-L-(8-Histidine) (Human)Patricia I. Dickson, M.D.CC
- Cyclosporin AMasonic Cancer Center, University of MinnesotaD
- ClofarabineMasonic Cancer Center, University of MinnesotaD
Citation
Floatz Terminal. Lsd in Lysosomal Storage Disease. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 11, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/lsd-lysosomal-storage-disease
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