Floatz Rating
B57/100
Confidence
Indicative
Sponsor
Instituto do Cancer do Estado de São Paulo
Modality
monoclonal_antibody
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02520141CT.gov Ramucirumab in Treating Patients With Advanced or Metastatic, Previously Treated Biliary Cancers That Cannot Be Removed by Surgery | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Gallbladder Cancer
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Nivolumab (this asset) | Instituto do Cancer do Estado de São Paulo | P2 | B · 57 |
| Fluorouracilum | Lisata Therapeutics, Inc. | P2 | BBB |
| Capecitabine | Merck Sharp & Dohme LLC | P3 | BB |
| Oxaliplatin | Tianjin Medical University Cancer Institute and Hospital | P3 | BB |
| Cyclophosphamide | Merck Sharp & Dohme LLC | P2 | BB |
| Epirubicin | Merck Sharp & Dohme LLC | P2 | BB |
| Sevoflurane | Tokyo Medical and Dental University | P4 | BB |
| Desflurane | Tokyo Medical and Dental University | P4 | BB |
| Docetaxel | Merck Sharp & Dohme LLC | P2 | BB |
+42 more in the Gallbladder Cancer cohort
Other indications for Nivolumab
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Renal Carcinoma | — | P4 | BBB · 72 |
| Metastatic Melanoma | — | P4 | BB · 70 |
| Non-Small Cell Lung Carcinoma | — | P4 | BB · 70 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Nivolumab in Gallbladder Cancer. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/nivolumab-gallbladder-cancer
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