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Floatz Rating
B63/100
Confidence
Indicative
v0.2
Sponsor
General Hospital of Shenyang Military Region
Modality
UNKNOWN
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
62High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Repeated Intravenous Thrombolysis for Ischemic Stroke With Medium to Large Vessel Occlusion Presenting Within 4.5 Hours of Onset With Prourokinase
Not Yet Recruiting
ProUrokinase for Mild Ischemic Cerebrovascular Events (PUMICE)
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Ischemic Stroke

AssetSponsorPhaseRating
Prourokinase (this asset)General Hospital of Shenyang Military RegionP3B · 63
TicagrelorSichuan Provincial People's HospitalP4BBB
CilostazolStanford UniversityP4BBB
Compound EdaravoneNanfang Hospital, Southern Medical UniversityP4BBB
3-N-BUTYLPHTHALIDENanfang Hospital, Southern Medical UniversityP4BBB
ArgatrobanSecond Affiliated Hospital, School of Medicine, Zhejiang UniversityP4BBB
TenecteplaseHackensack Meridian HealthP4BBB
ClopidogrelNanfang Hospital, Southern Medical UniversityP4BB
AspirinNanfang Hospital, Southern Medical UniversityP4BB

+42 more in the Ischemic Stroke cohort

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Prourokinase in Ischemic Stroke. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/prourokinase-ischemic-stroke

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