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(R)-(1-(4-Fluorophenyl)-6-((1-Methyl-1H-Pyrazol-4-Yl)Sulfonyl)-1,4,5,6,7,8-Hexahydro-4Ah-Pyrazolo(3,4-G)Isoquinolin-4A-Yl)(4-(Trifluoromethyl)Pyridin-2-Yl)Methanone

Peritoneal Neoplasm

Floatz Rating
BB64/100
Confidence
Indicative
v0.2
Sponsor
Corcept Therapeutics
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
52Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers
Recruiting
Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer
Active Not Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Peritoneal Neoplasm

AssetSponsorPhaseRating
(R)-(1-(4-Fluorophenyl)-6-((1-Methyl-1H-Pyrazol-4-Yl)Sulfonyl)-1,4,5,6,7,8-Hexahydro-4Ah-Pyrazolo(3,4-G)Isoquinolin-4A-Yl)(4-(Trifluoromethyl)Pyridin-2-Yl)Methanone (this asset)Corcept TherapeuticsP3BB · 64
CarboplatinEli Lilly and CompanyP3BBB
AdriamycinEli Lilly and CompanyP3BBB
NogitecanEli Lilly and CompanyP3BB
PatupiloneNovartis PharmaceuticalsP3BB
OxaliplatinSun Yat-sen UniversityP2/3BB
FluorouracilumAstraZenecaP2BB
OlaparibMerck Sharp & Dohme LLCP3B
PembrolizumabSeagen, a wholly owned subsidiary of PfizerP3B

+36 more in the Peritoneal Neoplasm cohort

Other indications for (R)-(1-(4-Fluorophenyl)-6-((1-Methyl-1H-Pyrazol-4-Yl)Sulfonyl)-1,4,5,6,7,8-Hexahydro-4Ah-Pyrazolo(3,4-G)Isoquinolin-4A-Yl)(4-(Trifluoromethyl)Pyridin-2-Yl)Methanone

IndicationSponsorPhaseRating
Cushing SyndromeP3BBB · 72
Pancreatic Ductal AdenocarcinomaP3BB · 64
Ovarian NeoplasmP3B · 60

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Citation

Floatz Terminal. (R)-(1-(4-Fluorophenyl)-6-((1-Methyl-1H-Pyrazol-4-Yl)Sulfonyl)-1,4,5,6,7,8-Hexahydro-4Ah-Pyrazolo(3,4-G)Isoquinolin-4A-Yl)(4-(Trifluoromethyl)Pyridin-2-Yl)Methanone in Peritoneal Neoplasm. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 13, 2026.
https://terminal.floatz.ai/assets/r-1-4-fluorophenyl-6-1-methyl-1h-pyrazol-4-ylsulfonyl-145678-hexahydro-4ah-pyrazolo34-gisoquinolin-4a-yl4-trifluoromethylpyridin-2-ylmethanone-peritoneal-neoplasm

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