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Floatz Rating
BB64/100
Confidence
Indicative
v0.2
Sponsor
Peking Union Medical College Hospital
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
67High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Study of Apatinib Combined With Letrozole With or Without Fluzoparib in Estrogen Receptor-Positive, Platinum-Sensitive Recurrent Ovarian Cancer Previously Treated With First-Line PARP Inhibitor
Terminated
Neoadjuvant Treatment of Ovarian Cancer With Fuzuloparib in Combination With Apatinib
Recruiting
HS-10502 Combination Treatment in Patients With Advanced Solid Tumors
Recruiting
Maintenance Therapy After Platinum-containing Chemotherapy in Patients With Recurrent Ovarian Cancer
Not Yet Recruiting
Fluzoparib With or Without Apatinib in Platinum-sensitive Relapsed Ovarian Cancer Previously Treated With PARPi
Unknown
The Efficacy and Safety of Fluzopril Combined With Apatinib in Maintenance Treatment of Platinum Resistant Recurrent Ovarian Cancer Patients
Not Yet Recruiting
Fluzoparib Combined With Apatinib in Relapsed Ovarian Carcinoma Maintenance Treatment
Not Yet Recruiting
Fluzopari Combined With Apatinib for the Neoadjuvant Treatment of Unresectable Ovarian Cancer
Unknown
Fluzoparib and Apatinib Versus Fluzoparib in Relapsed Ovarian Carcinoma Maintenance Treatment
Not Yet Recruiting
A Phase 2 Trial of Fluzoparib Combined With Apatinib Versus Fluzoparib Monotherapy in Treatment With Relapsed Ovarian Cancer Patients
Completed
Show 14 more trials
Apatinib Combined With Abraxane and Carboplatin or Cisplatinum as First-line Treatment for Epithelial Ovarian Cancer
Unknown
A Study of Fluzoparib±Apatinib Versus Placebo Maintenance Treatment in Patients With Advanced Ovarian Cancer Following Response on First-Line Platinum-Based Chemotherapy
Unknown
Apatinib and Etoposide Capsule Versus Apatinib in Patients With Platinum Resistant Ovarian Cancer
Unknown
Camrelizumab /Apatinib for Recurrent Platinum-resistant Ovarian Cancer
Unknown
Apatinib With Albumin-bound Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian Cancer
Unknown
Apatinib and Etoposide Capsule Versus Weekly Paclitaxel in Patients With Platinum Resistant Ovarian Cancer
Unknown
Clinical Study of Apatinib in the Treatment of Platinum Resistant Recurrent Ovarian Cancer
Terminated
Clinical Study of Apatinib in the Treatment of Advanced Ovarian Cancer After the Failure of Standard Chemotherapy
Unknown
Apatinib Combined With PLD vs PLD for Platinum-resistant Recurrent Ovarian Cancer
Unknown
Apatinib Plus Etoposide Versus Etoposide Alone for Platinum-resistant Recurrent Ovarian Cancer
Unknown
A Study of Apatinib Treatment in for Advanced Ovarian Cancer
Unknown
A Study of Fluzoparib Given in Combination With Apatinib in Ovarian or Breast Cancer Patients
Completed
The Use of 18F-ALF-NOTA-PRGD2 PET/CT Scan to Predict the Efficacy and Adverse Events of Apatinib in Malignancies.
Completed
Apatinib and Etoposide in Patients With Platinum Resistant or Refractory Ovarian Cancer
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
59High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Ovarian Cancer

AssetSponsorPhaseRating
Rivoceranib (this asset)Peking Union Medical College HospitalApprovedBB · 64
Tisotumab VedotinSeagen Inc.P2BB
TILInge Marie SvaneP2BB
OlaparibShandong UniversityP4BB
Cis-Diamminedichloroplatinum IiKalinski, Pawel, MD, PhDP3BB
AdriamycinGenmabP3BB
CarboplatinFudan UniversityP4BB
OTL-38On Target Laboratories, LLCP4BB
IrinotecanARCAGY/ GINECO GROUPP4BB

+42 more in the Ovarian Cancer cohort

Other indications for Rivoceranib

IndicationSponsorPhaseRating
Gastric CancerP4BBB · 73
Peripheral T-Cell Lymphoma, Not Otherwise SpecifiedP4BBB · 72
CancerP4BB · 69

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Rivoceranib in Ovarian Cancer. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/rivoceranib-ovarian-cancer

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