Floatz Rating
CC44/100
Confidence
Indicative
Sponsor
Children's Oncology Group
Modality
protein_peptide
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04978727CT.gov A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma | — | Active Not Recruiting | — | — | — |
NCT01250470CT.gov Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Anaplastic Astrocytoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Sargramostim (this asset) | Children's Oncology Group | P1 | CC · 44 |
| Cediranib | National Cancer Institute (NCI) | P2 | BBB |
| Irinotecan | City of Hope Medical Center | P2/3 | BBB |
| (+)-Vincristine | Novartis Pharmaceuticals | P2/3 | BB |
| Carboplatin | Oliver Jonas | P2 | BB |
| Trametinib | National Cancer Institute (NCI) | P4 | BB |
| Cintredekin Besudotox | INSYS Therapeutics Inc | P1/2 | BB |
| Ziv-Aflibercept | National Cancer Institute (NCI) | P2 | B |
| Cetuximab | University of Miami | P2 | B |
+42 more in the Anaplastic Astrocytoma cohort
Other indications for Sargramostim
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Melanoma | — | P3 | BBB · 72 |
| Cancer Of Unknown Primary Site | — | P2 | BBB · 72 |
| Chronic Myeloid Leukemia | — | P2 | BBB · 72 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Sargramostim in Anaplastic Astrocytoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/sargramostim-anaplastic-astrocytoma
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