Floatz Rating
B57/100
Confidence
Indicative
Sponsor
Vertex Pharmaceuticals Incorporated
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
45Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07231419CT.gov Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy | — | Recruiting | — | — | — |
NCT06696443CT.gov Evaluation of the Long-term Safety and Effectiveness of Suzetrigine (SUZ) in Participants With Painful Diabetic Peripheral Neuropathy (DPN) | — | Active Not Recruiting | — | — | — |
NCT06628908CT.gov Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Diabetic Neuropathy
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Suzetrigine (this asset) | Vertex Pharmaceuticals Incorporated | P3 | B · 57 |
| Duloxetine | Aga Khan University | P4 | A |
| Mirogabalin | Bangladesh Medical University | P4 | BBB |
| Gabapentin | Aziende Chimiche Riunite Angelini Francesco S.p.A | P4 | BBB |
| Capsaicin | Corporacion Parc Tauli | P4 | BBB |
| Lidocaine | Corporacion Parc Tauli | P4 | BBB |
| Pregabalin | Shandong Suncadia Medicine Co., Ltd. | P4 | BBB |
| (±)-2-(O-Chlorophenyl)-2-(Methylamino)Cyclohexanone | Irmandade da Santa Casa de Misericordia de Sao Paulo | P3 | BB |
| Tapentadol | Janssen Pharmaceutical K.K. | P3 | BB |
+42 more in the Diabetic Neuropathy cohort
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Suzetrigine in Diabetic Neuropathy. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/suzetrigine-diabetic-neuropathy
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