Floatz Rating
B57/100
Confidence
Indicative
Sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00210574CT.gov A Pilot Study of Topiramate in Childhood Absence Epilepsy | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Childhood Absence Epilepsy
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Topiramate (this asset) | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | P2 | B · 57 |
| Ethosuximide | Children's Hospital Medical Center, Cincinnati | P3 | BB |
| Lamotrigine | Children's Hospital Medical Center, Cincinnati | P3 | BB |
| Brivaracetam | UCB Biopharma SRL | P3 | B |
| Brivaracetam Film-Coated | UCB Biopharma SRL | P3 | B |
| Valproic Acid | Children's Hospital Medical Center, Cincinnati | P3 | B |
| Npt 2042 | NeuroPro Therapeutics, Inc. | P2 | CCC |
| Flunarizine Hcl | University of British Columbia | P2 | CCC |
| Bmb-101 | Bright Minds Biosciences Pty Ltd | P2 | NR |
Other indications for Topiramate
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Focal Epilepsy | — | P4 | A · 80 |
| Migraine With Aura | — | P4 | BBB · 78 |
| Migraine Without Aura | — | P4 | BBB · 78 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Topiramate in Childhood Absence Epilepsy. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/topiramate-childhood-absence-epilepsy
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