Floatz Rating
B60/100
Confidence
Indicative
Sponsor
Children's Hospital Medical Center, Cincinnati
Modality
Small molecule
Development Phase
Phase 3
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
48Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00088452CT.gov Childhood Absence Epilepsy Rx PK-PD-Pharmacogenetics Study | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Childhood Absence Epilepsy
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Valproic Acid (this asset) | Children's Hospital Medical Center, Cincinnati | P3 | B · 60 |
| Lamotrigine | Children's Hospital Medical Center, Cincinnati | P3 | BB |
| Ethosuximide | Children's Hospital Medical Center, Cincinnati | P3 | BB |
| Brivaracetam Film-Coated | UCB Biopharma SRL | P3 | B |
| Brivaracetam | UCB Biopharma SRL | P3 | B |
| Topiramate | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | P2 | B |
| Npt 2042 | NeuroPro Therapeutics, Inc. | P2 | CCC |
| Flunarizine Hcl | University of British Columbia | P2 | CCC |
| Bmb-101 | Bright Minds Biosciences Pty Ltd | P2 | NR |
Other indications for Valproic Acid
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Bipolar Disorder | — | P4 | BBB · 73 |
| Epilepsy | — | P4 | BBB · 73 |
| Bipolar I Disorder | — | P4 | BBB · 72 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Valproic Acid in Childhood Absence Epilepsy. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 13, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/valproic-acid-childhood-absence-epilepsy
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