Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
Northwestern University
Modality
UNKNOWN
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06410248CT.gov Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Grade II Glioma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Triapine (this asset) | Northwestern University | P1 | CC · 43 |
| Perampanel | Mayo Clinic | P4 | B |
| Pamiparib | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | P1/2 | B |
| FET | Thomas Hope | P2 | B |
| Selpercatinib | National Cancer Institute (NCI) | P2 | CCC |
| 2 (1H))-QUINOLINONE,6-(AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-4-(3-CHLOROPHENYL)-1-METHYL-,(+)- | National Cancer Institute (NCI) | P2 | CCC |
| Olaparib | National Cancer Institute (NCI) | P2 | CCC |
| Ivosidenib | National Cancer Institute (NCI) | P2 | CCC |
| Infigratinib | Helsinn Healthcare SA | P1/2 | CC |
+7 more in the Grade II Glioma cohort
Other indications for Triapine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Malignant Pancreatic Neoplasm | — | P2 | BB · 64 |
| Ovarian Carcinoma | — | P2 | BB · 64 |
| Cancer Of Unknown Primary Site | — | P1 | B · 58 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Triapine in Grade II Glioma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/triapine-grade-ii-glioma
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