Floatz Rating
CC46/100
Confidence
Indicative
Sponsor
Biogen
Modality
Small molecule
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
37High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02751905CT.gov Absorption, Metabolism, and Excretion Study of BIIB074 | — | Completed | — | — | — |
NCT02698267CT.gov Effect of Itraconazole on the Pharmacokinetics of BIIB074 | — | Completed | — | — | — |
NCT00964288CT.gov Effect of GSK1014802 on Electrical Hyperalgesia and Threshold Tracking in Healthy Subjects | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
73High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Neuralgia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Vixotrigine (this asset) | Biogen | P1 | CC · 46 |
| Dexmedetomidine | Universidad Juárez Autónoma de Tabasco | P4 | BBB |
| Midazolam | Minia University | P4 | BBB |
| Lidocaine | Ataturk University | P4 | BBB |
| Marcaine | Medipol University | P4 | BBB |
| (±)-2-(O-Chlorophenyl)-2-(Methylamino)Cyclohexanone | Margaux M. Salas, PhD | P4 | BBB |
| Capsaicin | University Hospital, Clermont-Ferrand | P4 | BBB |
| Pregabalin | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | P4 | BBB |
| Nabilone | Eldon Loh, MD | P4 | BBB |
+42 more in the Neuralgia cohort
Other indications for Vixotrigine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Trigeminal Neuralgia | — | P3 | B · 62 |
| Sciatica | — | P2 | B · 58 |
| Neuropathy, Painful | — | P1 | CC · 47 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Vixotrigine in Neuralgia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/vixotrigine-neuralgia-52026
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