Floatz Rating
B62/100
Confidence
Indicative
Sponsor
Biogen
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
49High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03070132CT.gov 802NP301 Efficacy and Safety Study of BIIB074 in Participants With Trigeminal Neuralgia | — | Withdrawn | — | — | — |
NCT03637387CT.gov 802NP302 Efficacy and Safety Study of BIIB074 in Participants With Trigeminal Neuralgia | — | Withdrawn | — | — | — |
NCT02951221CT.gov New Formulation and Food Effect Study of BIIB074 | — | Completed | — | — | — |
NCT02831517CT.gov PK and Safety Study of BIIB074 in Healthy Japanese and Caucasian Participants | — | Completed | — | — | — |
NCT02359344CT.gov PK & Tolerability of CNV1014802 in Young and Elderly Healthy Volunteers | — | Completed | — | — | — |
NCT01540630CT.gov A Phase IIa Withdrawal Study of CNV1014802 in Patients With Trigeminal Neuralgia | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Trigeminal Neuralgia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Vixotrigine (this asset) | Biogen | P3 | B · 62 |
| Neurotop | Beijing Tiantan Hospital | P4 | BB |
| Lidocaine | Beijing Tiantan Hospital | P4 | BB |
| (±)-2-(O-Chlorophenyl)-2-(Methylamino)Cyclohexanone | Vanderbilt University Medical Center | P4 | BB |
| Galcanezumab | Duke University | P4 | BB |
| Sufentanyl | Xiangya Hospital of Central South University | P4 | BB |
| Ondansetron | Xiangya Hospital of Central South University | P4 | BB |
| Oxcarbazepine | Abbasi Shaheed Hospital | P4 | B |
| Gabapentine | Rehman Medical Institute - RMI | P2/3 | B |
+24 more in the Trigeminal Neuralgia cohort
Other indications for Vixotrigine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Sciatica | — | P2 | B · 58 |
| Neuropathy, Painful | — | P1 | CC · 47 |
| Neuralgia | — | P1 | CC · 46 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Vixotrigine in Trigeminal Neuralgia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/vixotrigine-trigeminal-neuralgia
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