Floatz Rating
C37/100
Confidence
Indicative
Sponsor
Dana-Farber Cancer Institute
Modality
Cell therapy
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04678401CT.gov IS-free Treg HaploHCT | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Myelodysplastic Syndrome
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Treg-Enriched Donor Cell (this asset) | Dana-Farber Cancer Institute | P1 | C · 37 |
| Nivestim | City of Hope Medical Center | P4 | BB |
| Cyclophosphamide | Sawa Ito, MD | P4 | BB |
| Cytarabine | The First Affiliated Hospital of Soochow University | P4 | BB |
| Busulfanum | Sawa Ito, MD | P4 | BB |
| Idarubicin | OHSU Knight Cancer Institute | P4 | BB |
| Fludarabine | City of Hope Medical Center | P4 | BB |
| Daunomycin | OHSU Knight Cancer Institute | P3 | BB |
| Etoposide | Memorial Sloan Kettering Cancer Center | P3 | BB |
+42 more in the Myelodysplastic Syndrome cohort
Other indications for Treg-Enriched Donor Cell
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Disease Related To Hematopoietic Stem Cell Transplant | — | P1 | CC · 43 |
| Graft Versus Host Disease | — | P1 | CC · 43 |
| Acute Myeloid Leukemia | — | P1 | CC · 43 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Treg-Enriched Donor Cell in Myelodysplastic Syndrome. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 14, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/treg-enriched-donor-cell-myelodysplastic-syndrome
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