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Floatz Rating
CC46/100
Confidence
Indicative
v0.2
Sponsor
PMV Pharmaceuticals, Inc
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.
Recruiting
A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors
Withdrawn
PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates
Completed
Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors
Completed
Effects of Dabrafenib on the Single Dose Pharmacokinetics (PK) of Rosuvastatin and Midazolam
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
59High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Cancer

AssetSponsorPhaseRating
Rosuvastatin (this asset)PMV Pharmaceuticals, IncP1CC · 46
NabiximolsJazz PharmaceuticalsP3BBB
RivoceranibJiangsu HengRui Medicine Co., Ltd.P4BB
OxaliplatinSixth Affiliated Hospital, Sun Yat-sen UniversityP4BB
PyridoxolM.D. Anderson Cancer CenterP4BB
FluorouracilumSixth Affiliated Hospital, Sun Yat-sen UniversityP3BB
EpirubicinZhejiang Provincial People's HospitalP3BB
Cis-Diamminedichloroplatinum IiInSilico Medicine Hong Kong LimitedP4BB
TrametinibCancer Research UKP2/3BB

+42 more in the Cancer cohort

Other indications for Rosuvastatin

IndicationSponsorPhaseRating
Inherited Lipid Metabolism DisorderP4BBB · 77
HyperlipidemiaP4BBB · 72
Abdominal Obesity-Metabolic SyndromeP4BBB · 72

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Rosuvastatin in Cancer. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 14, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/rosuvastatin-cancer-111251

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